Every Tadalafil tablet consists of 10mg of Tadalafil. Cialis tablets are yellow, film-coated, and almond-shaped; produced in 5, 10, or 20 mg doses. In the United States, tadalafil has Food and Drug Administration approval and became available in December, 2003 as the third impotence pill after sildenafil (Viagra) and vardenafil (Levitra). In researches at the reception of single dose of 5 or 10 mgs of AUC increased in 2 times for patients with the par function of buds of easy(Cl of kreatinine 51-80 mls/of mines) or middle(Cl of kreatinine 31-50 mls/of mines) degree of expressed. For patients with the last stage of kidney insufficiency, being at the reception of single dose of tadalafil 10 or 20 mgs there was a 2-multiple increase of C _ mах and increase of AUC in 2,7-4,1 time. It is necessary to mean that sexual activity has a potential risk for patients with cardiovascular diseases. Therefore treatment of erectile disfunction, including with the use, it is not necessary to conduct for men with cardiovascular diseases at that sexual activity is not recommended. It is necessary to take into account that at the obstruction of the left ventricle (for example aortic stenosis hypertrophic subaortic stenosis) patients can react on the action of including the inhibitors. A 10 mg dose of Tadalafil is capable enough to treat patients suffering from minor hepatic impairment. However, the dose of Tadalafil required to treat the patients afflicted with acute hepatic impairment is undetermined. Once a patient takes a tablet of 10mg Tadalafil, this drug is not drained out of the patient's body until around 2 days after its consumption. This drug has been developed for men and hence, should not be taken by a woman. However, it can be taken by a woman to treat pulmonary arterial hypertension. If taken after consulting a physician, it can treat male impotency. There are rare reports about the origin of erection proceeding more than 4 ч, and priapism (sickly erection lasting more than 6 ч), at the use of connections of this class. Ill-timed treatment can bring a penis over to the irreversible damage of fabrics. In case if erection lasts more than 4 ч, a patient is necessary immediately to visit a doctor. Tadalafil is capable of inhibiting the action of phosphodiesterase type 5 in order to treat the patients suffering from erectile dysfunction. It falls in the category of ‘oral treatment'. The patients suffering from erectile dysfunction are advised to take a 10 mg Tadalafil tablet before getting involved in any form of sexual activity.
